286 Is there a place for CTX with cystic fibrosis?

Airway clearance in cystic fibrosis: is there a better way?

The pathophysiology of cystic fibrosis (CF) lung disease is initiated by dysfunction of the CF transmembrane conductance regulator protein, leading to dysregulation of the salt and water content of the airway surface liquid. Abnormal airway surface liquid compromises mucociliary clearance and airway defenses against infection. An exaggerated inflammatory response leads to an influx of large num...

Is there still a gender gap in cystic fibrosis?

OBJECTIVES Previous studies have shown that female patients with cystic fibrosis (CF) have a significantly poorer prognosis than male patients. Such studies investigating gender-related differences have generally combined data from several centers. The aim of this study was to determine whether with modern aggressive treatment of CF this is still true when care is standardized within a single c...

Is there still a place for thrombectomy?

Malignancy is known to be a prothrombotic condition , and some antitumor drugs may amplify the hyper-coagulable tendency. We present a female patient with cancer, who developed acute coronary syndrome (ACS) due to occlusive intracoronary thrombus without underlying atherosclerosis. A 59-year-old woman with metastatic breast cancer diagnosed 2 years ago, paraneoplastic syndrome and steroid diabe...

Is there a place for animal experiments?

Is There a Place for Post-method Pedagogy in the Educational Context of Iran: Voices of EFL Teachers

In an attempt to liberate teachers from deficiencies of the conventional methods, Kumaravadivelu (1994) proposed the concept of “post method condition” to overcome the challenges caused by the very nature of methods. The literature regarding post-method pedagogy has indicated that most of the studies focus on its theoretical aspect, while the practical realization has been largely untouched. To...